PDZD2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PDZD2.
Immunogen
A synthetic peptide corresponding to human PDZD2.
Sequence
PITQDNAVLHLPLC
Host
Goat
Theoretical MW (kDa)
304
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PDZD2
Entrez GeneID
23037Protein Accession#
NP_055837Gene Name
PDZD2
Gene Alias
AIPC, KIAA0300, PAPIN, PDZK3, PIN1
Gene Description
PDZ domain containing 2
Omim ID
610697Gene Ontology
HyperlinkGene Summary
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq
Other Designations
PDZ domain containing 3|activated in prostate cancer protein|plakophilin-related armadillo repeat protein-interacting PDZ protein-like
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Interactome
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Disease
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Publication Reference
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PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.
Deguchi M, Iizuka T, Hata Y, Nishimura W, Hirao K, Yao I, Kawabe H, Takai Y.
The Journal of Biological Chemistry 2000 Sep; 275(38):29875.
Application:IF, WB-Ti, WB-Tr, Monkey, Rat, COS, NRK cells, Rat brains, Rat bronchial epithelial cells.
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PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.
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