SNTA1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
SNTA1 polyclonal antibody (Cat # PAB6532) (0.01 ug/mL) staining of human muscle lysate (35 ug protein in RIPA buffer) with (A) and without (B) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SNTA1.
Immunogen
A synthetic peptide corresponding to human SNTA1.
Sequence
ASGRRAPRTGLLE-C
Host
Goat
Theoretical MW (kDa)
53.9
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
SNTA1 polyclonal antibody (Cat # PAB6532) (0.01 ug/mL) staining of human muscle lysate (35 ug protein in RIPA buffer) with (A) and without (B) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SNTA1
Entrez GeneID
6640Protein Accession#
NP_003089.1Gene Name
SNTA1
Gene Alias
SNT1, TACIP1, dJ1187J4.5
Gene Description
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
Omim ID
601017Gene Ontology
HyperlinkGene Summary
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq
Other Designations
OTTHUMP00000030650|acidic alpha 1 syntrophin|dystrophin-associated protein A1, 59kD, acidic component|pro-TGF-alpha cytoplasmic domain-interacting protein 1|syntrophin, alpha 1 (dystrophin-associated protein A1, 59kD, acidic component)
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Interactome
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Disease
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Publication Reference
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A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface.
Fernandez-Larrea J, Merlos-Suarez A, Urena JM, Baselga J, Arribas J.
Molecular Cell 1999 Apr; 3(4):423.
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A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface.
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