OSBPL1A polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
OSBPL1A polyclonal antibody (Cat # PAB6513) staining (0.5 ug/mL) of human muscle lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of OSBPL1A.
Immunogen
A synthetic peptide corresponding to human OSBPL1A.
Sequence
C-YWDRNYFNLPDIY
Host
Goat
Theoretical MW (kDa)
50.3, 108
Reactivity
Human
Specificity
This antibody is expected to recognize all three human isoforms of this protein (represented by NP_060500, NP_542164, NP_579802).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
OSBPL1A polyclonal antibody (Cat # PAB6513) staining (0.5 ug/mL) of human muscle lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — OSBPL1A
Entrez GeneID
114876Protein Accession#
NP_060500;NP_542164;NP_579802Gene Name
OSBPL1A
Gene Alias
FLJ10217, ORP-1, ORP1, OSBPL1B
Gene Description
oxysterol binding protein-like 1A
Omim ID
606730Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq
Other Designations
OSBP-related protein 1|oxysterol binding protein-like 1B|oxysterol-binding protein-like 1A|oxysterol-binding protein-related protein 1
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Interactome
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Disease
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Publication Reference
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The OSBP-related protein family in humans.
Lehto M, Laitinen S, Chinetti G, Johansson M, Ehnholm C, Staels B, Ikonen E, Olkkonen VM.
Journal of Lipid Research 2001 Aug; 42(8):1203.
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The OSBP-related protein family in humans.
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