NBEA polyclonal antibody
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More Files
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Western Blot (Transfected lysate)
NBEA polyclonal antibody (Cat # PAB6509) staining (1 ug/mL) of (Lane 1) untransfected HEK 293T (Bosc 23) cells (Lane 2) HEK 293T (Bosc 23) cells transfected with mouse NBEA. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NBEA.
Immunogen
A synthetic peptide corresponding to human NBEA.
Sequence
C-DFNRWHYEHQNRY
Host
Goat
Theoretical MW (kDa)
328
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
NBEA polyclonal antibody (Cat # PAB6509) staining (1 ug/mL) of (Lane 1) untransfected HEK 293T (Bosc 23) cells (Lane 2) HEK 293T (Bosc 23) cells transfected with mouse NBEA. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NBEA
Entrez GeneID
26960Protein Accession#
NP_056493.3Gene Name
NBEA
Gene Alias
BCL8B, LYST2
Gene Description
neurobeachin
Omim ID
604889Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. Alternatively spliced transcript variants may exist, but their full-length nature has not been determined. [provided by RefSeq
Other Designations
lysosomal trafficking regulator 2
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Interactome
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Disease
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Publication Reference
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Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic.
Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, Kilimann MW.
The Journal of Neuroscience 2000 Dec; 20(23):8551.
Application：IHC, IF, WB-Ti, WB-Ce, Mouse, Rat, Monkey, Brain, PC-12, COS-7 cells.
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Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic.
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