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Last updated: 2016/12/4
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KALRN polyclonal antibody

  • Catalog # : PAB6507
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of KALRN.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human KALRN.
  • Sequence:
  • C-RWHLGPGDPFSTYV
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 192
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is expected to recognize isoform 2 (NP_0.03938.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (0.5-1.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • KALRN polyclonal antibody (Cat # PAB6507) (0.5 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8997
  • Gene Name:
  • KALRN
  • Gene Alias:
  • DUET,FLJ16443,HAPIP,TRAD,duo
  • Gene Description:
  • kalirin, RhoGEF kinase
  • Gene Summary:
  • Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000165775,huntingtin-associated protein interacting protein (duo),serine/threonine kinase with Dbl- and pleckstrin homology domains
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