EPS8 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
EPS8 polyclonal antibody (Cat # PAB6473, 5 ug/mL) staining of paraffin embedded human breast Carcinoma. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of EPS8.
Immunogen
A synthetic peptide corresponding to human EPS8.
Sequence
C-SGVESFDEGSSH
Host
Goat
Theoretical MW (kDa)
91.9
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
EPS8 polyclonal antibody (Cat # PAB6473, 5 ug/mL) staining of paraffin embedded human breast Carcinoma. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EPS8
Entrez GeneID
2059Protein Accession#
NP_004438Gene Name
EPS8
Gene Alias
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Gene Description
epidermal growth factor receptor pathway substrate 8
Omim ID
600206Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals.
Fazioli F, Minichiello L, Matoska V, Castagnino P, Miki T, Wong WT, Di Fiore PP.
The EMBO Journal 1993 Oct; 12(10):3799.
Application：IP, IP-WB, WB-Tr, Mouse, NIH/3T3, 32D cells.
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Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals.
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