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Western Blot

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

Protein Accession#

Gene Name

FBXL10

Gene Alias

CXXC2, Fbl10, JHDM1B, KDM2B, PCCX2

Gene Description

F-box and leucine-rich repeat protein 10

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq

Other Designations

JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein|jumonji C domain-containing histone demethylase 1B|protein containing CXXC domain 2