FBXL6 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FBXL6.
Immunogen
A synthetic peptide corresponding to human FBXL6.
Sequence
CLEQLLTSPSPS
Host
Goat
Theoretical MW (kDa)
58.6, 57.9
Specificity
This antibody is expected to recognize reported human isoforms (NP_0.36294.1 and NP_078831.3).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — FBXL6
Entrez GeneID
26233Protein Accession#
NP_0.36294.1;NP_078831.3Gene Name
FBXL6
Gene Alias
FBL6, FBL6A, PP14630
Gene Description
F-box and leucine-rich repeat protein 6
Omim ID
609076Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq
Other Designations
F-box protein Fbl6
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Interactome
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Publication Reference
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A family of mammalian F-box proteins.
Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
Current Biology 1999 Oct; 9(20):1180.
Application:WB-Tr, Insect cells, Skp1 protein.
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A family of mammalian F-box proteins.
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