LDLRAP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
LDLRAP1 polyclonal antibody (Cat # PAB6434) staining (3 ug/mL) of human liver lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of LDLRAP1.
Immunogen
A synthetic peptide corresponding to human LDLRAP1.
Sequence
DALKSAGRALIRS-C
Host
Goat
Theoretical MW (kDa)
33.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
LDLRAP1 polyclonal antibody (Cat # PAB6434) staining (3 ug/mL) of human liver lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — LDLRAP1
Entrez GeneID
26119Protein Accession#
NP_056442.1Gene Name
LDLRAP1
Gene Alias
ARH, ARH1, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705
Gene Description
low density lipoprotein receptor adaptor protein 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq
Other Designations
LDL receptor adaptor protein|OTTHUMP00000008526|autosomal recessive hypercholesterolemia protein
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Interactome
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Pathway
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Disease
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Publication Reference
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ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.
He G, Gupta S, Yi M, Michaely P, Hobbs HH, Cohen JC.
The Journal of Biological Chemistry 2002 Nov; 277(46):44044.
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ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2.
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