USP15 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of USP15.
Immunogen
A synthetic peptide corresponding to C-terminus of human USP15.
Sequence
NDIENENCMHTN
Host
Goat
Theoretical MW (kDa)
109
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-3.8 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
USP15 polyclonal antibody (Cat # PAB6412) (3.8 ug/mL) staining of paraffin embedded human liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — USP15
Entrez GeneID
9958Protein Accession#
NP_006304Gene Name
USP15
Gene Alias
KIAA0529, MGC131982, MGC149838, MGC74854, UNPH4
Gene Description
ubiquitin specific peptidase 15
Omim ID
604731Gene Ontology
HyperlinkGene Summary
Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).[supplied by OMIM
Other Designations
deubiquitinating enzyme|ubiquitin specific protease 15
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Interactome
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Disease
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Publication Reference
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Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases.
Baker RT, Wang XW, Woollatt E, White JA, Sutherland GR.
Genomics 1999 Aug; 59(3):264.
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Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases.
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