REV1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of REV1.
Immunogen
A synthetic peptide corresponding to human REV1.
Sequence
C-VLQQTYGSTLKVT
Host
Goat
Theoretical MW (kDa)
138
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — REV1
Entrez GeneID
51455Protein Accession#
NP_057400Gene Name
REV1
Gene Alias
FLJ21523, MGC163283, MGC26225, REV1L
Gene Description
REV1 homolog (S. cerevisiae)
Omim ID
606134Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq
Other Designations
OTTHUMP00000161216|REV1- like|REV1-like
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Interactome
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Disease
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Publication Reference
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Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain.
Masuda Y, Takahashi M, Tsunekuni N, Minami T, Sumii M, Miyagawa K, Kamiya K.
The Journal of Biological Chemistry 2001 May; 276(18):15051.
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Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain.
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