PCGF2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
PCGF2 polyclonal antibody (Cat # PAB6398) staining (1 ug/mL) of human lung lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PCGF2.
Immunogen
A synthetic peptide corresponding to human PCGF2.
Sequence
C-KMTVNGAPVPPLT
Host
Goat
Theoretical MW (kDa)
37.8
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PCGF2 polyclonal antibody (Cat # PAB6398) staining (1 ug/mL) of human lung lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PCGF2
Entrez GeneID
7703Protein Accession#
NP_009075Gene Name
PCGF2
Gene Alias
MEL-18, MGC10545, RNF110, ZNF144
Gene Description
polycomb group ring finger 2
Omim ID
600346Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq
Other Designations
ring finger protein 110|zinc finger protein 144
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Interactome
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Disease
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Publication Reference
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Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.
Ishida A, Asano H, Hasegawa M, Koseki H, Ono T, Yoshida MC, Taniguchi M, Kanno M.
Gene 1993 Jul; 129(2):249.
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Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif.
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