GPS1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GPS1.
Immunogen
A synthetic peptide corresponding to human GPS1.
Sequence
C-PANSQSRMSTNM
Host
Goat
Theoretical MW (kDa)
59.1, 55.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
GPS1 polyclonal antibody (Cat # PAB6395) staining (0.5 ug/mL) of human testis lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPS1
Entrez GeneID
2873Protein Accession#
NP_004118Gene Name
GPS1
Gene Alias
COPS1, CSN1, MGC71287
Gene Description
G protein pathway suppressor 1
Omim ID
601934Gene Ontology
HyperlinkGene Summary
This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Arabidopsis FUS6/COP11 homolog
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Interactome
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Publication Reference
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Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells.
Spain BH, Bowdish KS, Pacal AR, Staub SF, Koo D, Chang CY, Xie W, Colicelli J.
Molecular and Cellular Biology 1996 Dec; 16(12):6698.
Application:WB-Ce, WB-Tr, Human, Yeast, Mammalian cells, Yeast cells.
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Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells.
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