RIG polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of RIG.
Immunogen
A synthetic peptide corresponding to C-terminus of human RIG.
Sequence
TLSVVGPHPKPCIL
Host
Goat
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
RIG polyclonal antibody (Cat # PAB6389)(3.8 ug/mL) staining of paraffin embedded human uterus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DKK3
Entrez GeneID
27122Protein Accession#
AAC35996.1Gene Name
DKK3
Gene Alias
REIC
Gene Description
dickkopf homolog 3 (Xenopus laevis)
Omim ID
605416Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
RIG-like 5-6|RIG-like 7-1|dickkopf 3|dickkopf homolog 3
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Interactomes
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Diseases
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Publication Reference
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Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma.
Ligon AH, Pershouse MA, Jasser SA, Yung WK, Steck PA.
Oncogene 1997 Mar; 14(9):1075.
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Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma.
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