TRIM55 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TRIM55.
Immunogen
A synthetic peptide corresponding to human TRIM55.
Sequence
C-HIFSFSWLNSLNE
Host
Goat
Theoretical MW (kDa)
60.5, 50.8, 26.8
Reactivity
Human
Specificity
This antibody is expected to recognize isoforms 1, 3 and 4 (NP_908973.1, NP_908974.1and NP_908975.1 resp.).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRIM55
Entrez GeneID
84675Protein Accession#
NP_908973.1;NP_908974.1;NP_908975.1Gene Name
TRIM55
Gene Alias
MURF-2, RNF29
Gene Description
tripartite motif-containing 55
Omim ID
606469Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
muscle specific ring finger 2|ring finger protein 29
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Interactome
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Disease
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Publication Reference
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Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.
Centner T, Yano J, Kimura E, McElhinny AS, Pelin K, Witt CC, Bang ML, Trombitas K, Granzier H, Gregorio CC, Sorimachi H, Labeit S.
Journal of Molecular Biology 2001 Mar; 306(4):717.
Application:IEM, Mouse, Mouse hearts.
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Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.
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