TRIM8 polyclonal antibody
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More Files
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of TRIM8.
Immunogen
A synthetic peptide corresponding to C-terminus of human TRIM8.
Sequence
C-YGQPSTKHYVTS
Host
Goat
Theoretical MW (kDa)
61.5
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
TRIM8 polyclonal antibody (Cat # PAB6352) (4 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRIM8
Entrez GeneID
81603Protein Accession#
NP_112174Gene Name
TRIM8
Gene Alias
GERP, RNF27
Gene Description
tripartite motif-containing 8
Omim ID
606125Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes. [provided by RefSeq
Other Designations
glioblastoma expressed ring finger protein|ring finger protein 27|tripartite motif protein TRIM8
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Interactomes
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Diseases
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Publication Reference
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A novel RING finger-B box-coiled-coil protein, GERP.
Vincent SR, Kwasnicka DA, Fretier P.
Biochemical and Biophysical Research Communications 2000 Dec; 279(2):482.
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A novel RING finger-B box-coiled-coil protein, GERP.
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