CDYL polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
CDYL polyclonal antibody (Cat # PAB6311) staining (1 ug/mL) of human testis lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CDYL.
Immunogen
A synthetic peptide corresponding to human CDYL.
Sequence
C-SMLKYLQRKIDEF
Host
Goat
Theoretical MW (kDa)
60.6, 45.1
Reactivity
Human
Specificity
This antibody is expected to recognize all three reported isoforms (NP_004815.2, NP_736607.1, NP_736608.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CDYL polyclonal antibody (Cat # PAB6311) staining (1 ug/mL) of human testis lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDYL
Entrez GeneID
9425Protein Accession#
NP_004815.2;NP_736607.1;NP_736608.1Gene Name
CDYL
Gene Alias
CDYL1, DKFZp586C1622, MGC131936
Gene Description
chromodomain protein, Y-like
Omim ID
603778Gene Ontology
HyperlinkGene Summary
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq
Other Designations
CDY-like, autosomal|OTTHUMP00000015984|bA620A17.2 (chromodomain protein, Y chromosome-like)|chromodomain protein, Y chromosome-like|chromodomain protein, Y chromosome-like, isoform b|testis-specific chromodomain Y-like protein
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Interactome
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Disease
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Publication Reference
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Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.
Lahn BT, Page DC.
Nature Genetics 1999 Apr; 21(4):429.
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Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.
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