SART3 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SART3.
Immunogen
A synthetic peptide corresponding to human SART3.
Sequence
C-MSNADFAKLFLRK
Host
Goat
Theoretical MW (kDa)
110
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
SART3 polyclonal antibody (Cat # PAB6299) staining (0.01 ug/mL) of Jurkat cell lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SART3
Entrez GeneID
9733Protein Accession#
NP_055521.1Gene Name
SART3
Gene Alias
DSAP1, KIAA0156, MGC138188, P100, RP11-13G14, TIP110, p110, p110(nrb)
Gene Description
squamous cell carcinoma antigen recognized by T cells 3
Omim ID
611684Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq
Other Designations
tat-interacting protein of 110 kDa
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Interactome
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Publication Reference
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p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor.
Bell M, Schreiner S, Damianov A, Reddy R, Bindereif A.
The EMBO Journal 2002 Jun; 21(11):2724.
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p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor.
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