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Last updated: 2016/12/4
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SETDB2 polyclonal antibody

  • Catalog # : PAB6288
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SETDB2.
  • Immunogen:
  • A synthetic peptide corresponding to human SETDB2.
  • Sequence:
  • GEKNGDAKTFWME-C
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 81.9, 80.7
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (0.3-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • SETDB2 polyclonal antibody (Cat # PAB6288) staining (0.5 ug/mL) of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • SETDB2
  • Gene Alias:
  • C13orf4,CLLD8,CLLL8,DKFZp586I0123,DKFZp761J1217,KMT1F
  • Gene Description:
  • SET domain, bifurcated 2
  • Gene Summary:
  • Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM
  • Other Designations:
  • CLLL8 protein,OTTHUMP00000018417
  • Gene Pathway
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