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Last updated: 2017/12/10
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PUF60 polyclonal antibody

  • Catalog # : PAB6268
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PUF60.
  • Immunogen:
  • A synthetic peptide corresponding to human PUF60.
  • Sequence:
  • C-YDQERFDNSDLSA
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 59.9, 58.2, 55.7
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported human isoforms (as represented by NP_055096.2; NP_510965.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • PUF60 polyclonal antibody (Cat # PAB6268) staining (1 ug/mL) of A-431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_510965.1;NP_055096.2
  • Gene Name:
  • PUF60
  • Gene Alias:
  • FIR,FLJ31379,RoBPI,SIAHBP1
  • Gene Description:
  • poly-U binding splicing factor 60KDa
  • Gene Summary:
  • The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq
  • Other Designations:
  • FBP interacting repressor,Ro ribonucleoprotein binding protein 1,Ro ribonucleoprotein-binding protein 1,fuse-binding protein-interacting repressor,poly-U binding splicing factor PUF60,pyrimidine tract binding splicing factor,siah binding protein 1
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