CENPE polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CENPE.
Immunogen
A synthetic peptide corresponding to human CENPE.
Sequence
HASSGKDVPECKTQ
Host
Goat
Theoretical MW (kDa)
316
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CENPE
Entrez GeneID
1062Protein Accession#
NP_001804Gene Name
CENPE
Gene Alias
KIF10
Gene Description
centromere protein E, 312kDa
Omim ID
117143Gene Ontology
HyperlinkGene Summary
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. [provided by RefSeq
Other Designations
Centromere autoantigen E (312kD)|centromere protein E|centromere protein E (312kD)|kinesin family member 10
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Interactome
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Disease
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Publication Reference
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CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.
Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW.
The EMBO Journal 1991 May; 10(5):1245.
Application：IF, WB-Ce, Human, HeLa cells.
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CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.
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