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Last updated: 2017/8/13
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PRDM16 polyclonal antibody

  • Catalog # : PAB6224
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PRDM16.
  • Immunogen:
  • A synthetic peptide corresponding to human PRDM16.
  • Sequence:
  • C-TSESGAFHPINHL
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 140, 138
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • PRDM16
  • Gene Alias:
  • KIAA1675,MEL1,MGC166915,PFM13
  • Gene Description:
  • PR domain containing 16
  • Gene Summary:
  • The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • MDS1/EVI1-like,PR-domain zinc finger protein 16,transcription factor MEL1
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