CABP1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CABP1.
Immunogen
A synthetic peptide corresponding to human CABP1.
Sequence
GNCVKYPLRNLS
Host
Goat
Theoretical MW (kDa)
26, 19.4
Reactivity
Human
Specificity
This antibody is expected to recognize both human isoforms.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CABP1 polyclonal antibody (Cat # PAB6223) staining (1 ug/mL) of human brain lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CABP1
Entrez GeneID
9478Protein Accession#
NP_004267;NP_112482Gene Name
CABP1
Gene Alias
CALBRAIN, HCALB_BR
Gene Description
calcium binding protein 1
Omim ID
605563Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this gene was only detected in retina and brain. Study of the mouse homolog demonstrated that groups of cells expressing this protein are located in the center or inner border of the inner unclear layer of retina. Three alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
calcium binding protein 5|caldendrin
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Interactome
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Publication Reference
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Calbrain, a novel two EF-hand calcium-binding protein that suppresses Ca2+/calmodulin-dependent protein kinase II activity in the brain.
Yamaguchi K, Yamaguchi F, Miyamoto O, Sugimoto K, Konishi R, Hatase O, Tokuda M.
The Journal of Biological Chemistry 1999 Feb; 274(6):3610.
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Calbrain, a novel two EF-hand calcium-binding protein that suppresses Ca2+/calmodulin-dependent protein kinase II activity in the brain.
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