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Last updated: 2016/12/4
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TXNRD1 polyclonal antibody

  • Catalog # : PAB6199
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TXNRD1.
  • Immunogen:
  • A synthetic peptide corresponding to human TXNRD1.
  • Sequence:
  • TKRSGASILQAGC
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 54.7, 54.7, 70.9
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TXNRD1 polyclonal antibody (Cat # PAB6199) staining (0.1 ug/mL) of human placenta lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7296
  • Gene Name:
  • TXNRD1
  • Gene Alias:
  • GRIM-12,MGC9145,TR,TR1,TRXR1,TXNR
  • Gene Description:
  • thioredoxin reductase 1
  • Gene Summary:
  • This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq
  • Other Designations:
  • KM-102-derived reductase-like factor,oxidoreductase,thioredoxin reductase GRIM-12
  • Gene Pathway
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