CPT1B polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CPT1B.
Immunogen
A synthetic peptide corresponding to human CPT1B.
Sequence
C-DIADLFQVPKAYS
Host
Goat
Theoretical MW (kDa)
87.8, 83.9, 78.8
Reactivity
Human
Specificity
This antibody is expected to recognize human isoforms a (as represented by NP_004368.1, NP_689451.1 and NP_689452.1), but not isoform b (NP_689453.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CPT1B polyclonal antibody (Cat # PAB6190) (3.8 ug/mL) staining of paraffin embedded human heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CPT1B
Entrez GeneID
1375Protein Accession#
NP_004368.1;NP_689451.1;NP_689452.1Gene Name
CPT1B
Gene Alias
CPT1-M, KIAA1670, M-CPT1, MCCPT1
Gene Description
carnitine palmitoyltransferase 1B (muscle)
Omim ID
601987Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq
Other Designations
CPTI, muscle|carnitine O-palmitoyltransferase I, mitochondrial muscle isoform|carnitine palmitoyltransferase 1A (muscle)|carnitine palmitoyltransferase 1B
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Interactome
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Pathway
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Disease
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Publication Reference
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Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.
Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H.
Biochimica et Biophysica Acta 1996 Jun; 1307(2):157.
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Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.
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