ARPC1B polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
ARPC1B polyclonal antibody (Cat # PAB6170) staining (2 ug/mL) of human liver lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ARPC1B.
Immunogen
A synthetic peptide corresponding to human ARPC1B.
Sequence
AYHSFLVEPISCH
Host
Goat
Theoretical MW (kDa)
40.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ARPC1B polyclonal antibody (Cat # PAB6170) staining (2 ug/mL) of human liver lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ARPC1B
Entrez GeneID
10095Protein Accession#
NP_005711Gene Name
ARPC1B
Gene Alias
ARC41, p40-ARC, p41-ARC
Gene Description
actin related protein 2/3 complex, subunit 1B, 41kDa
Omim ID
604223Gene Ontology
HyperlinkGene Summary
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. [provided by RefSeq
Other Designations
ARP2/3 protein complex subunit p41|actin related protein 2/3 complex subunit 1B|actin related protein 2/3 complex, subunit 1A (41 kD)|actin related protein 2/3 complex, subunit 1B (41 kD)
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Interactome
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Pathway
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Publication Reference
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The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ.
The Journal of Cell Biology 1997 Jul; 138(2):375.
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The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
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