IRF6 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
IRF6 polyclonal antibody (Cat # PAB6150) staining (0.2 ug/mL) of human ovary lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of IRF6.
Immunogen
A synthetic peptide corresponding to human IRF6.
Sequence
C-TPSMQLPPALPPQ
Host
Goat
Theoretical MW (kDa)
53.1
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.2-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
IRF6 polyclonal antibody (Cat # PAB6150) staining (0.2 ug/mL) of human ovary lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IRF6
Entrez GeneID
3664Protein Accession#
NP_006138Gene Name
IRF6
Gene Alias
LPS, OFC6, PIT, PPS, VWS
Gene Description
interferon regulatory factor 6
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. [provided by RefSeq
Other Designations
OTTHUMP00000034677
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Interactome
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Disease
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Publication Reference
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Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes.
Kondo S, Schutte BC, Richardson RJ, Bjork BC, Knight AS, Watanabe Y, Howard E, de Lima RL, Daack-Hirsch S, Sander A, McDonald-McGinn DM, Zackai EH, Lammer EJ, Aylsworth AS, Ardinger HH, Lidral AC, Pober BR, Moreno L, Arcos-Burgos M, Valencia C, Houdayer C, Bahuau M, Moretti-Ferreira D, Richieri-Costa A, Dixon MJ, Murray JC.
Nature Genetics 2002 Oct; 32(2):285.
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Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes.
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