ADAM8 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
ADAM8 polyclonal antibody (Cat # PAB6146) (1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ADAM8.
Immunogen
A synthetic peptide corresponding to C-terminus of human ADAM8.
Sequence
C-QRKQGAGAPTAP
Host
Goat
Theoretical MW (kDa)
88.8, 78.8
Reactivity
Human
Specificity
This antibody is expected to recognise isoform 1 and 3 (NP_001100.3; NP_001157962.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:1000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ADAM8 polyclonal antibody (Cat # PAB6146) (1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADAM8
Entrez GeneID
101Protein Accession#
NP_001100Gene Name
ADAM8
Gene Alias
CD156, MGC134985, MS2
Gene Description
ADAM metallopeptidase domain 8
Omim ID
602267Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
CD156a antigen|OTTHUMP00000020792|a disintegrin and metalloproteinase domain 8|cell surface antigen MS2
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Interactome
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Disease
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Publication Reference
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CD156 (human ADAM8): expression, primary amino acid sequence, and gene location.
Yoshiyama K, Higuchi Y, Kataoka M, Matsuura K, Yamamoto S.
Genomics 1997 Apr; 41(1):56.
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CD156 (human ADAM8): expression, primary amino acid sequence, and gene location.
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