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Last updated: 2017/6/25
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AXIN1 polyclonal antibody

  • Catalog # : PAB6140
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of AXIN1.
  • Immunogen:
  • A synthetic peptide corresponding to human AXIN1.
  • Sequence:
  • C-FEEKIIGKVEKVD
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 95.6, 91.7
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:128000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • AXIN1 polyclonal antibody (Cat # PAB6140, 3.8 ug/mL) staining of paraffin embedded human adrenal cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8312
  • Protein Accession#:
  • NP_003493.1;NP_851393.1
  • Gene Name:
  • AXIN1
  • Gene Alias:
  • AXIN,MGC52315
  • Gene Description:
  • axin 1
  • Gene Summary:
  • This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • axis inhibition protein 1,axis inhibitor 1,fused, mouse, homolog of
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