PSCDBP polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PSCDBP.
Immunogen
A synthetic peptide corresponding to human PSCDBP.
Sequence
SLQRLLQHSSNGN-C
Host
Goat
Theoretical MW (kDa)
40
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
PSCDBP polyclonal antibody (Cat # PAB6131) staining (1 ug/mL) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CYTIP
Entrez GeneID
9595Protein Accession#
NP_004279.3Gene Name
CYTIP
Gene Alias
B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP
Gene Description
cytohesin 1 interacting protein
Omim ID
604448Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.[provided by RefSeq
Other Designations
cytohesin binder and regulator|cytohesin binding protein HE|cytohesin-1 interacting protein|pleckstrin homology, Sec7 and coiled-coil domains, binding protein|pleckstrin homology, Sec7 and coiled/coil domains, binding protein
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Interactome
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Disease
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Publication Reference
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Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.
Tang P, Cheng TP, Agnello D, Wu CY, Hissong BD, Watford WT, Ahn HJ, Galon J, Moss J, Vaughan M, O'Shea JJ, Gadina M.
PNAS 2002 Mar; 99(5):2625.
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Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.
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