VAV2 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of VAV2.
Immunogen
A synthetic peptide corresponding to human VAV2.
Sequence
ETEAKYYRTLEDIEC
Host
Goat
Theoretical MW (kDa)
101, 97.0
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (1-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
VAV2 polyclonal antibody (Cat # PAB6123) staining (1.5 ug/mL) of 293 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — VAV2
Entrez GeneID
7410Protein Accession#
NP_003362Gene Name
VAV2
Gene Alias
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Gene Description
vav 2 guanine nucleotide exchange factor
Omim ID
600428Gene Ontology
HyperlinkGene Summary
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022509|Protein vav-2|oncogene VAV2|vav 2 oncogene
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1.
Henske EP, Short MP, Jozwiak S, Bovey CM, Ramlakhan S, Haines JL, Kwiatkowski DJ.
Annals of Human Genetics 1995 Jan; 59(1):25.
Application:WB-Re, WB-Ti, Human, Recombinant proteins, Tissues.
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Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1.
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