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Last updated: 2017/6/25
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TBL1X/TBL1XR1 polyclonal antibody

  • Catalog # : PAB6110
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TBL1X/TBL1XR1.
  • Immunogen:
  • A synthetic peptide corresponding to human TBL1X, TBL1XR1.
  • Sequence:
  • SASDGSVCVLDLRK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 62.5, 57.0, 55.6
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is also expected to recognize the human protein TBLR1 (NP_078941), which is very similar.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:4000)
    Western blot (3-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • The TBL1X/TBL1XR1 polyclonal antibody (Cat # PAB6110) staining (4 ug/mL) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6907
  • Protein Accession#:
  • NP_005638.1 (Gene ID : 6907);NP_078941.2 (Gene ID : 79718)
  • Gene Name:
  • TBL1X
  • Gene Alias:
  • EBI,SMAP55,TBL1
  • Gene Description:
  • transducin (beta)-like 1X-linked
  • Gene Summary:
  • The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq
  • Other Designations:
  • F-box-like/WD repeat-containing protein TBL1X,OTTHUMP00000022880,transducin beta-like 1X
  • Gene Information
  • Protein Accession#:
  • NP_005638.1 (Gene ID : 6907);NP_078941.2 (Gene ID : 79718)
  • Gene Name:
  • TBL1XR1
  • Gene Alias:
  • C21,DC42,FLJ12894,IRA1,TBLR1
  • Gene Description:
  • transducin (beta)-like 1 X-linked receptor 1
  • Gene Summary:
  • The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. [provided by RefSeq
  • Other Designations:
  • TBL1-related protein 1,nuclear receptor co-repressor/HDAC3 complex subunit
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