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Last updated: 2017/8/13
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NUMB polyclonal antibody

  • Catalog # : PAB6102
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of NUMB.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human NUMB.
  • Sequence:
  • C-PFSSDLQKTFEIEL
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 70.8, 65.9, 69.4, 64
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody is expected to recognize all reported isoforms (NP_001005743.1, 001005744.1, NP_0.03735, NP_001005745.1). It is also likely to cross-react with Numblike (NUMBL, GeneID: 9253) which has a very similar C-Terminus, although this has not yet been tested experimentally.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.03-0.1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • NUMB polyclonal antibody (Cat # PAB6102) staining (0.03 ug/mL) of mouse brain lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8650
  • Protein Accession#:
  • NP_001005743.1;001005744.1;NP_0.03735;NP_001005745.1
  • Gene Name:
  • NUMB
  • Gene Alias:
  • S171
  • Gene Description:
  • numb homolog (Drosophila)
  • Gene Summary:
  • The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • numb homolog
  • Interactome
  • Interactome
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