ELMO3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
ELMO3 polyclonal antibody (Cat # PAB6101) staining (2 ug/mL) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ELMO3.
Immunogen
A synthetic peptide corresponding to human ELMO3.
Sequence
TNFNFCYDCSIAEP
Host
Goat
Theoretical MW (kDa)
70
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ELMO3 polyclonal antibody (Cat # PAB6101) staining (2 ug/mL) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ELMO3
Entrez GeneID
79767Protein Accession#
NP_078988.2Gene Name
ELMO3
Gene Alias
CED-12, CED12, ELMO-3, FLJ13824
Gene Description
engulfment and cell motility 3
Omim ID
606422Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq
Other Designations
ced-12 homolog 3
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Interactome
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Publication Reference
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CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS.
Cell 2001 Oct; 107(1):27.
Application：WB-Tr, Mouse, LR73 cells.
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CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
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