PACSIN1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PACSIN1.
Immunogen
A synthetic peptide corresponding to human PACSIN1.
Sequence
SSSYDEASLAPEET-C
Host
Goat
Theoretical MW (kDa)
51.1
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PACSIN1 polyclonal antibody (Cat # PAB6089) staining (1 ug/mL) of human brain (hippocampus) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescenc.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PACSIN1
Entrez GeneID
29993Protein Accession#
NP_065855.1Gene Name
PACSIN1
Gene Alias
KIAA1379, SDPI
Gene Description
protein kinase C and casein kinase substrate in neurons 1
Omim ID
606512Gene Ontology
HyperlinkOther Designations
OTTHUMP00000016231|syndapin I
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Interactome
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Disease
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Publication Reference
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PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains.
Modregger J, DiProspero NA, Charles V, Tagle DA, Plomann M.
Human Molecular Genetics 2002 Oct; 11(21):2547.
Application:IF, WB-Ti, Human, Brain.
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PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains.
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