FGR polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
FGR polyclonal antibody (Cat # PAB6066) staining (0.5 ug/mL) of mouse spleen extracts (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FGR.
Immunogen
A synthetic peptide corresponding to human FGR.
Sequence
C-TSAEPQYQPGDQT
Host
Goat
Theoretical MW (kDa)
59.5
Reactivity
Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
FGR polyclonal antibody (Cat # PAB6066) staining (0.5 ug/mL) of mouse spleen extracts (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — FGR
Entrez GeneID
2268Protein Accession#
NP_005239Gene Name
FGR
Gene Alias
FLJ43153, MGC75096, SRC2, c-fgr, c-src2, p55c-fgr, p58c-fgr
Gene Description
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
Omim ID
164940Gene Ontology
HyperlinkGene Summary
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000003601|OTTHUMP00000003602|OTTHUMP00000003603|c-fgr protooncogene|c-src-2 proto-oncogene|p55-c-fgr protein|proto-oncogene tyrosine-protein kinase FGR
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Primary structure of the human fgr proto-oncogene product p55c-fgr.
Katamine S, Notario V, Rao CD, Miki T, Cheah MS, Tronick SR, Robbins KC.
Molecular and Cellular Biology 1988 Jan; 8(1):259.
Application：IP, Monkey, COS-1 cells.
-
Primary structure of the human fgr proto-oncogene product p55c-fgr.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com