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Last updated: 2016/10/16
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BAIAP2 polyclonal antibody

  • Catalog # : PAB6057
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of BAIAP2.
  • Immunogen:
  • A synthetic peptide corresponding to human BAIAP2.
  • Sequence:
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 57.4
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize only human isoform 1 according to NP_059344.1.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • BAIAP2 polyclonal antibody (Cat # PAB6057) staining (1 ug/mL) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • BAIAP2
  • Gene Alias:
  • BAP2,IRSP53
  • Gene Description:
  • BAI1-associated protein 2
  • Gene Summary:
  • The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
  • Other Designations:
  • insulin receptor substrate p53
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