PRAM1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PRAM1.
Immunogen
A synthetic peptide corresponding to human PRAM1.
Sequence
DFCDPLENQPLPLGR
Host
Goat
Theoretical MW (kDa)
73.8
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:8000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
PRAM1 polyclonal antibody (Cat # PAB6052) staining (2 ug/mL) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PRAM1
Entrez GeneID
84106Protein Accession#
NP_115528Gene Name
PRAM1
Gene Alias
MGC39864, PRAM-1
Gene Description
PML-RARA regulated adaptor molecule 1
Omim ID
606466Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). [provided by RefSeq
Other Designations
PML-RARA target gene encoding an Adaptor Molecule-1
-
Interactome
-
Publication Reference
-
PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.
Moog-Lutz C, Peterson EJ, Lutz PG, Eliason S, Cave-Riant F, Singer A, Di Gioia Y, Dmowski S, Kamens J, Cayre YE, Koretzky G.
The Journal of Biological Chemistry 2001 Jun; 276(25):22375.
Application:IP, IP-WB, WB-Ce, Human, Monkey, COS-7, NB4 cells.
-
PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com