TNS1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TNS1.
Immunogen
A synthetic peptide corresponding to C-terminus of human TNS1.
Sequence
C-VSKVMLNAGQKR
Host
Goat
Theoretical MW (kDa)
186
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
TNS1 polyclonal antibody (Cat # PAB6040) (4 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TNS1
Entrez GeneID
7145Protein Accession#
NP_072174.3Gene Name
TNS1
Gene Alias
DKFZp586K0617, MGC88584, MST091, MST122, MST127, MSTP122, MSTP127, MXRA6, TNS
Gene Description
tensin 1
Omim ID
600076Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined. [provided by RefSeq
Other Designations
Matrix-remodelling-associated protein 6|matrix-remodelling associated 6|tensin
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Interactome
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Disease
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Publication Reference
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Molecular characterization of human tensin.
Chen H, Ishii A, Wong WK, Chen LB, Lo SH.
The Biochemical Journal 2000 Oct; 351 Pt 2:403.
Application:WB, Human, Breast cancer cells, Prostate cancer cells.
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Molecular characterization of human tensin.
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