SH2B1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SH2B1.
Immunogen
A synthetic peptide corresponding to human SH2B1.
Sequence
PFGASDCVTDHLP
Host
Goat
Theoretical MW (kDa)
70.8
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SH2B1
Entrez GeneID
25970Protein Accession#
NP_056318.1Gene Name
SH2B1
Gene Alias
DKFZp547G1110, FLJ30542, KIAA1299, SH2-B, SH2B
Gene Description
SH2B adaptor protein 1
Omim ID
608937Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
SH2 domain-containing putative adapter SH2-B|SH2-B alpha signaling protein|SH2-B gamma signaling protein|SH2-B homolog
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Interactome
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Pathway
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Disease
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Publication Reference
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SH2-B family members differentially regulate JAK family tyrosine kinases.
O'Brien KB, O'Shea JJ, Carter-Su C.
J Biol Chem 2001 Dec; 277(10):8673.
Application：IP, Mouse, 3T3-F442A cells.
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SH2-B family members differentially regulate JAK family tyrosine kinases.
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