ORC6L polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
HEK293 overexpressing ORC6L and probed with ORC6L polyclonal antibody (Cat # PAB6026) (mock transfection in first lane), tested by Origene.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ORC6L.
Immunogen
A synthetic peptide corresponding to C-terminus of human ORC6L.
Sequence
C-ENAASAQKATAE
Host
Goat
Theoretical MW (kDa)
28.1
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
HEK293 overexpressing ORC6L and probed with ORC6L polyclonal antibody (Cat # PAB6026) (mock transfection in first lane), tested by Origene. -
Gene Info — ORC6L
Entrez GeneID
23594Protein Accession#
NP_055136.1Gene Name
ORC6L
Gene Alias
ORC6
Gene Description
origin recognition complex, subunit 6 like (yeast)
Omim ID
607213Gene Ontology
HyperlinkGene Summary
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq
Other Designations
origin recognition complex subunit 6|origin recognition complex, subunit 6 homolog-like
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Interactome
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Pathway
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