RTEL1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RTEL1.
Immunogen
A synthetic peptide corresponding to N-terminus of human RTEL1.
Sequence
VDFPFQPYKCQQEYMTKVLE
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity chromatography
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.09% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — RTEL1
Entrez GeneID
51750Gene Name
RTEL1
Gene Alias
C20orf41, DKFZp434C013, KIAA1088, NHL, RTEL, bK3184A7.3
Gene Description
regulator of telomere elongation helicase 1
Omim ID
608833Gene Ontology
HyperlinkGene Summary
In mice, inactivation of the Rtel (regulator of telomere length) gene has been shown to cause chromosome breaks, fusions, and telomere loss. In addition, Rtel is required for telomere elongation. Therefore, the mouse Rtel gene regulates chromosome stability and telomere length. This gene is the human ortholog of the mouse Rtel gene, so its protein product may play similar roles in humans. It is located in a gene-rich cluster on chromosome 20, with other potential tumor-related genes, such as TNFRSF6B. Multiple transcript variants encoding different isoforms have been described for this gene, although the full-length nature of not all variants is known. [provided by RefSeq
Other Designations
OTTHUMP00000031577|OTTHUMP00000184892|regulator of telomere length
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