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Last updated: 2016/12/4
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RAB8A polyclonal antibody

  • Catalog # : PAB5542
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of RAB8A.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human RAB8A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4218
  • Gene Name:
  • RAB8A
  • Gene Alias:
  • MEL,RAB8
  • Gene Description:
  • RAB8A, member RAS oncogene family
  • Gene Summary:
  • The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq
  • Other Designations:
  • mel transforming oncogene,mel transforming oncogene (RAB8 homolog),mel transforming oncogene (derived from cell line NK14),mel transforming oncogene (derived from cell line NK14)- RAB8 homolog,ras-associated protein RAB8
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