ITGAV polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ITGAV.
Immunogen
A synthetic peptide corresponding to C-terminus of human ITGAV.
Host
Rabbit
Reactivity
Chicken, Human, Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ITGAV
Entrez GeneID
3685Gene Name
ITGAV
Gene Alias
CD51, DKFZp686A08142, MSK8, VNRA
Gene Description
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Omim ID
193210Gene Ontology
HyperlinkGene Summary
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
Integrin, alpha-V (vitronectin receptor, alpha polypeptide)|antigen identified by monoclonal antibody L230|integrin alpha-V
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Interactome
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Disease
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