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Last updated: 2016/12/4
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FBLN5 polyclonal antibody

  • Catalog # : PAB5361
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of FBLN5.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human FBLN5.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Gene Name:
  • FBLN5
  • Gene Alias:
  • ARMD3,DANCE,EVEC,FIBL-5,FLJ90059,UP50
  • Gene Description:
  • fibulin 5
  • Gene Summary:
  • The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq
  • Other Designations:
  • developmental arteries and neural crest epidermal growth factor-like,urine p50 protein
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