EEF1A1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EEF1A1.
Immunogen
A synthetic peptide corresponding to C-terminus of human EEF1A1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — EEF1A1
Entrez GeneID
1915Gene Name
EEF1A1
Gene Alias
CCS-3, CCS3, EEF-1, EEF1A, EF-Tu, EF1A, FLJ25721, GRAF-1EF, HNGC:16303, LENG7, MGC102687, MGC131894, MGC16224, PTI1, eEF1A-1
Gene Description
eukaryotic translation elongation factor 1 alpha 1
Omim ID
130590Gene Ontology
HyperlinkGene Summary
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq
Other Designations
CTCL tumor antigen|EF1a-like protein|OTTHUMP00000016736|OTTHUMP00000063804|OTTHUMP00000063805|cervical cancer suppressor 3|elongation factor 1 alpha subunit|elongation factor 1-alpha|elongation factor Tu|eukaryotic translation elongation factor 1 alpha 1-
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Interactome
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Publication Reference
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Degradation of newly synthesized polypeptides by ribosome-associated RACK1/JNK/eEF1A2 complex.
Gandin V, Gutierrez GJ, Brill LM, Varsano T, Feng Y, Aza-Blanc P, Au Q, McLaughlan S, Ferreira TA, Alain T, Sonenberg N, Topisirovic I, Ronai ZA.
Molecular and Cellular Biology 2013 Jul; 33(13):2510.
Application：WB, Human, HEK 293T cells.
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Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression.
Scaggiante B, Dapas B, Bonin S, Grassi M, Zennaro C, Farra R, Cristiano L, Siracusano S, Zanconati F, Giansante C, Grassi G.
British Journal of Cancer 2012 Jan; 106(1):166.
Application：WB, Human, DU-145, PC-3, LNCaP, PZHPV-7 cells.
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Degradation of newly synthesized polypeptides by ribosome-associated RACK1/JNK/eEF1A2 complex.
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