ASXL1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ASXL1.
Immunogen
A synthetic peptide corresponding to C-terminus of human ASXL1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen-specific affinity chromatography
Recommend Usage
ELISA
Western Blot (1 ug/mL for 2hrs)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ASXL1
Entrez GeneID
171023Gene Name
ASXL1
Gene Alias
KIAA0978, MGC117280, MGC71111
Gene Description
additional sex combs like 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000030592|additional sex combs like 1
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Interactome
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Disease
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