CSH1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native CSH1.
Immunogen
Native purified human CSH1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Native Protein.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
Enzyme Immunoassay
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Gene Info — CSH1
Entrez GeneID
1442Gene Name
CSH1
Gene Alias
CSA, CSMT, FLJ75407, PL
Gene Description
chorionic somatomammotropin hormone 1 (placental lactogen)
Omim ID
150200Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq
Other Designations
CS-1|choriomammotropin|chorionic somatomammotropin A|chorionic somatomammotropin hormone 1|hCS-A|placental lactogen
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Interactome
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Pathway
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Disease
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Publication Reference
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Human Placental Tissue Contains A Placental Lactogen-Derived Vasoinhibin.
Hülya Markl-Hahn, Leon Neugebauer, Livia Lenke, Sarah Ecker, Tamara Merz, Oscar McCook, Noura Khoder, Cosima Brucker, Peter Radermacher, Christiane Waller, Carmen Clapp, Thomas Bertsch, Jakob Triebel.
Journal of the Endocrine Society 2022 Feb; 6(4):bvac029.
Application:WB-Ce, Human, Human placenta.
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Human Placental Tissue Contains A Placental Lactogen-Derived Vasoinhibin.
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