GRP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GRP.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human GRP.
Sequence
VPLPAGGGTVLTKMYPRGNHWAVGHLM
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against synthetic peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Enzyme Immunoassay
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Gene Info — GRP
Entrez GeneID
2922Gene Name
GRP
Gene Alias
BN, GRP-10, preproGRP, proGRP
Gene Description
gastrin-releasing peptide
Omim ID
137260Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
bombesin|neuromedin C|pre-progastrin releasing peptide
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Interactome
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Pathway
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Disease
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