Formalin-fixed and paraffin-embedded placenta tissue reacted with SPPL2A polyclonal antibody (Cat # PAB4907) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
This gene is a member of the signal peptide peptidase-like protease (SPPL) family and encodes an endosomal membrane protein with a protease associated (PA) domain. This protein plays a role in innate and adaptive immunity. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq
intramembrane cleaving protease,intramembrane protease 3,presenilin-like protein 2