SPPL2A polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
The SPPL2A polyclonal antibody (Cat # PAB4907) is used in Western blot to detect SPPL2A in Jurkat cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded placenta tissue reacted with SPPL2A polyclonal antibody (Cat # PAB4907) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SPPL2A.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SPPL2A.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The SPPL2A polyclonal antibody (Cat # PAB4907) is used in Western blot to detect SPPL2A in Jurkat cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded placenta tissue reacted with SPPL2A polyclonal antibody (Cat # PAB4907) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SPPL2A
Entrez GeneID
84888Protein Accession#
Q8TCT8Gene Name
SPPL2A
Gene Alias
IMP3, PSL2
Gene Description
signal peptide peptidase-like 2A
Omim ID
608238Gene Ontology
HyperlinkGene Summary
This gene is a member of the signal peptide peptidase-like protease (SPPL) family and encodes an endosomal membrane protein with a protease associated (PA) domain. This protein plays a role in innate and adaptive immunity. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq
Other Designations
intramembrane cleaving protease|intramembrane protease 3|presenilin-like protein 2
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Interactome
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Publication Reference
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Novel class of polytopic proteins with domains associated with putative protease activity.
Grigorenko AP, Moliaka YK, Korovaitseva GI, Rogaev EI.
Biochemistry 2002 Jul; 67(7):826.
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Novel class of polytopic proteins with domains associated with putative protease activity.
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